Cytokines and diseases. Cytokines and liver diseases.

Interleukin-1 Family Cytokines in Liver Diseases

The gene encoding IL-1 was sequenced more than 30 years ago, and many related cytokines, such as IL-18, IL-33, IL-36, IL-37, IL-38, IL-1 receptor antagonist (IL-1Ra), and IL-36Ra, have since been identified. IL-1 is a potent proinflammatory cytokine and is involved in various inflammatory diseases. Other IL-1 family ligands are critical for the development of diverse diseases, including inflamm...

Cytokines in infectious diseases

Interest in cytokines in infection is increasing exponentially both because of the central role these peptide molecules have in immune responses in a wide spectrum of human responses in health and disease1 and because they are likely to be pivotal in the development of new therapies and vaccine strategies. Immunity to infections and attempts by pathogens to avoid the host defence system provide...

Cytokines in chronic respiratory diseases

Cytokines are small, secreted proteins that control immune responses. Within the lung, they can control host responses to injuries or infection, resulting in clearance of the insult, repair of lung tissue, and return to homeostasis. Problems can arise when this response is over exuberant and/or cytokine production becomes dysregulated. In such cases, chronic and repeated inflammatory reactions ...

Cytokines in Chronic Neurodegenerative Diseases

Cytokines and eicosanoids in rheumatic diseases.